Research and Development

Activities & Voices

Monomer Synthesis
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Establishment of manufacturing process applying small molecule expertise
By taking advantage of experience accumulated over 40 years in process development for advanced intermediates and APIs, we are capable of establishing and managing the manufacturing process for high-quality amidites, other raw materials, and oligonucleotides.
The quality of amidites is vitally important in the quality control of oligonucleotides.
An industrial amidite manufacturing process that removes some critical impurities leads to the improvement of amidite quality, as well as crude oligonucleotide quality and purification efficiency. To closely control oligonucleotide quality, Sumitomo Chemical synthesizes hundreds of samples of amidite impurities that may cause impurity problems in oligonucleotides.