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HOME > NEWS > Sumitomo successfully completed its first GMP production of guide RNA used for CRISPR-Cas9 system in its brand-new oligonucleotide plant in Oita, Japan
  • Nov 1, 2023

    Sumitomo successfully completed its first GMP production of guide RNA used for CRISPR-Cas9 system in its brand-new oligonucleotide plant in Oita, Japan

    Sumitomo Chemical is pleased to announce the successful manufacturing of guide RNA (gRNA) for genome editing and achieving 86.5% purity. This marks the first GMP production of gRNA in its newly constructed Oita Plant (Oita, Japan). This was a direct scale-up from laboratory scale, without a trial batch, leveraging Sumitomo’s Standard Manufacturing Method that can be applied to most gRNAs.


    The Oita Plant, which started its operation from August 2023, is a state-of-the-art facility equipped for manufacturing long synthetic RNAs such as gRNAs used for CRISPR-Cas9 system. Building on this manufacturing success, Sumitomo will continue to supply high-quality gRNA for genome editing and contribute to the widespread adoption of genome-editing therapy.


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